Cytogenetic Study of Ethylene Glycol Monomethylether Using Micronucleus Test.
نویسندگان
چکیده
منابع مشابه
The micronucleus test as an in vivo cytogenetic method.
Methods are currently being explored which would permit the application of cytogenetic procedures such as metaphase and anaphase analyses to in vivo mammalian systems in order that due consideration may be given to metabolic activation or detoxification reactions which might affect the mutagenic or clastogenic (chromosome breaking) potential of environmental agents under study. It has been reco...
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The aim of this study was to evaluate tri-ethylene glycol mono-methacrylate (TEGMA) in terms of dermatological allergic reaction using a Guinea Pig Maximization Test. Skin reaction was evaluated according to the criteria of International Contact Dermatitis Research Group. TEGMA, as a constituent in new primers, has been reported to contribute to a priming ability similar to that of highly purif...
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---・-A micronucleus test using BDFi male mice was conducted in order to evaluate the in vive mutagenicity of mofezolac (N-22). N-22 was orally administered at doses of 75, 150, 300 arid 600 mglkg, with a sampling time of 24 hr. The frequency of polychromatic erythrocytes with micronuclei was O,07-O,08% in the groups treated with N-22 and did not differ markedly from that of the vehicle control ...
متن کاملpropylene glycol , and ethylene glycol - based antifreeze
of AF performance. that contain EG has been reponed to result in irreversible damage to renal, hepatic, cardiovascular, and central nervous systems, and is a cause of death in household pets and other animals.2-4 It is not known why some animals ingest EGcontaining products. Although there are reports suggesting that the "sweet" taste of EG, and of products containing it, may lead to ingestion ...
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Clinical and forensic laboratories frequently have to face cases of severe intoxication from ethylene glycol, because of its wide availability, and thus its use as an additive in various housekeeping and commercial products such as anti-freezing agent, car batteries and solvents for dyes. The majority of ethylene glycol poisonings is related to suicide attempts (intentional ingestion) and to mi...
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ژورنال
عنوان ژورنال: Sangyo Igaku
سال: 1993
ISSN: 0047-1879,1881-1302
DOI: 10.1539/joh1959.35.286